BFS Line

BRIEF INTRODUCTION

BFS (Blow-Fill-Seal) Machine is an advanced aseptic packaging technology that directly forms containers from pharmaceutical-grade PP/PE pellets and completes blowing, filling, and sealing under fully aseptic conditions throughout the entire process. This technology minimizes manual intervention and environmental exposure, effectively reducing the risk of contamination and ensuring product safety and consistency. It is an ideal solution for the aseptic production of liquid pharmaceutical preparations.
Product Description Product Video Related News Download Information

Standalone Machine Positioning

The machine independently completes aseptic blow molding, filling, and sealing processes, meeting GMP requirements for standalone aseptic production.


Applicable Packaging & Specifications

  • Packaging Type: Plastic PE / PP aseptic bottles

  • Aseptic Bottle Volume Range: 5 mL, 10 mL

  • Maximum Output: Up to 6,000 bottles/hour

  • Mold Size: Single mold with 40 cavities

  • Module Configuration: 4 sets × 10 cavities


Process Flow

Material feeding → In-machine processes: plastic pellet heating and extrusionbottle blowing and formingfilling sealing cutting → bottle discharge


Key Performance Parameters

image.png


Structure & GMP Design

  • Extrusion, forming, filling, and sealing are completed under aseptic conditions within an integrated system, minimizing personnel, environmental, and material contamination, and ensuring product safety.

  • Pharmaceutical-grade plastic resins are used, featuring excellent heat resistance and low permeability to steam and air, and complying with EU GMP and USP standards.

  • The machine supports CIP (Clean-in-Place) and SIP (Sterilize-in-Place), ensuring equipment cleanliness and sterility in compliance with GMP requirements.


Control System

  • An advanced electronic control system equipped with Schneider or ABB touch-screen HMI, offering an intuitive interface for easy parameter setting and monitoring.

  • High-precision control components are utilized, including ratio pressure controllers, optocoupler relays, miniature relays, valve terminals, servo drives, and servo motors.

  • Multiple safety protection devices—such as overload thermal relays, motor protectors, and safety door interlocks—are provided to ensure operational safety and stable machine performance.

  • All production steps—including heating, extrusion, blowing, forming, filling, and sealing—are fully automated to minimize manual intervention.


Utility Requirements

image.png


GIVE US A MESSAGE

Submit
%{tishi_zhanwei}%