PRODUCTS

HOME
PRODUCTS
Filling Line
Infusion Bottle Filling Line

PRODUCTS

Infusion Bottle Filling Line

BRIEF INTRODUCTION

Infusion bottle filling production line is an integrated pharmaceutical manufacturing system covering the complete process flow, including bottle unscrambling, washing, drying, sterilization, filling, stopper insertion, capping (crimping/screw capping), and labeling. The line consists of the JKGP Bottle Unscrambler, JKQCX Rotary Ultrasonic Bottle Washer, JKRX Tunnel Sterilization Drying Oven, JKGS Filling and Capping Machine, JKZ Starwheel Positioning Capping Machine, and JKLT Vertical Self-Adhesive Labeling Machine, ensuring stable operation and smooth line integration. It is suitable for infusion bottles with volumes ranging from 20–500 mL. Multiple bottle sizes can be handled through simple mold changeover, allowing flexible adaptation to diverse pharmaceutical production requirements.

YouTube

Product Description Product Video Related News Download Information

Product Positioning

Designed to meet GMP-grade production requirements for sterile pharmaceutical products, covering the complete process of bottle washing → sterilization → filling → stoppering/capping → labeling.

Applicable Packaging Type & Specifications

Packaging Type: Infusion bottles
Fill Volume Range: 50 – 500 mL
Maximum Output: Up to 6,000 bottles/hour
(verified under 100 mL glass infusion bottles, liquid product conditions)

Process Flow

Bottle infeed → Ultrasonic washing (two-water / one-air, 50–100 bottles/min) → Dry heat sterilization (hot air 300 °C × 5 min) → Filling (servo-driven with peristaltic pump, ±0.5% accuracy) → Stoppering / capping (acceptance rate ≥99.9%) → Vertical labeling (accuracy ±1 mm)

Core Modules

Control System & Data Integrity

The entire line is controlled by a Siemens PLC with an industrial touch-screen HMI, supporting user access management and fast recipe changeover.
All operating data are monitored in real time with interlinked alarms, and electronic batch records can be generated automatically.
The system supports MES integration and complies with 21 CFR Part 11 data integrity requirements.

Washing & Sterilization Strategy

The washing area supports interchangeable molds, with laser-cut drum structures for rapid format change
Sterilization tunnel options: dry heat 300 °C × 15 min or 250 °C × 30 min, achieving endotoxin reduction ≥3 log
Cooling zone airflow of 0.6–0.7 m/s, with an automatic overpressure balancing system to ensure cleanroom stability